Fatty acids-carotenoid complex: An effective anti-TB agent from the chlorella growth factor-extracted spent biomass of Chlorella vulgaris.

Ethnopharmacological Relevance: The multidrug-resistant (MDR) pathogen, Mycobacterium tuberculosis, still remains as one of the major threat to mankind, despite the availability of a live attenuated vaccine and effective antibiotics. Marine microalgae, at all times, act as a key resource for valuable therapeutic compounds with limited side effects.

Aim Of The Study: The present explorative attempt is to isolate the biomolecules of pharmacological importance from the marine microalgae, Chlorella vulgaris, and to evaluate its effect on the ever dreadful disease, Tuberculosis.

Ectoine biosynthesis genes from the deep sea halophilic eubacteria, Bacillus clausii NIOT-DSB04: Its molecular and biochemical characterization.

Ectoine, the most prominent osmolyte in nature, is a vital compatible solute present in halophilic bacterium. It protects the cellular biomolecules of the halophilic bacteria and retains their intrinsic function from extreme circumstances. In the current research, ectoine biosynthesis gene cluster (ectABC) in Bacillus clausii NIOT-DSB04 was expressed heterologically in E.

Early Detection of Skin Cancer Using Melanoma Segmentation technique.

The significance of pattern recognition techniques is widely enhanced in image processing and medical applications. Thus, lesion segmentation method is an essential technique of pattern recognition algorithms to detect the melanoma skin cancer in patients at earliest stage, otherwise, in further stages it becomes one of the deadliest disease and its mortality rate is very high. Therefore, a precise melanoma segmentation technique is introduced based on the Gradient and Feature Adaptive Contour (GFAC) model to detect melanoma skin cancer in earliest stage and diagnosis of dermoscopic images.

Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives.

A series of novel naphthoquinone amide derivatives of the bioactive quinones, plumbagin, juglone, menadione and lawsone, with various amino acids were synthesized. The compounds were characterized by (1)H NMR, (13)C NMR, Mass, IR and elemental analysis. All the compounds were evaluated for their anticancer activity against HeLa and SAS cancer cell lines and 3D-QSAR indicated the presence of electron donating group near sulphur enhanced the activity against HeLa cells.

Vapor-phase toxicity of Derris scandens Benth.-derived constituents against four stored-product pests.

The vapor-phase toxicity of Derris scandens Benth.-derived constituents was evaluated against four stored-product pests ( Callosobruchus chinensis L., Sitophilus oryzae L.