Publications by authors named "T Sprenger"
Background And Purpose: Neuromix is a fast, motion robust multi-contrast sequence capable of providing all diagnostic contrasts in ∼3.5 minutes. However, more evaluation is needed across the various contrasts compared to gold standard, optimized sequences routinely used in the clinic.
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- Overuse of CT angiography (CTA) for minor neurological issues can cause unnecessary radiation exposure and may require follow-up MRI for proper diagnosis.
- A study evaluated the effectiveness of a fast MRI protocol called NeuroMix, combined with MRA, against CTAH for patients within 24 hours, with results indicating that the MRI approach was equivalent or superior in most cases.
- The findings suggest that the new MRI techniques can provide better or similar diagnostic information in 95% of instances, reducing reliance on CTA for certain patient populations.
Herein, we report the synthesis and sensing characteristics of 4,4'-methoxy-substituted BODIPY fluorescent probes (O-BODIPYs) 3, 4 and 5 equipped with differently sized benzo-crown ethers (cf. Scheme 1, 3 (benzo-15-crown-5), 4 (benzo-18-crown-6) and 5 (benzo-21-crown7)). O-BODIPYs 3, 4 and 5 exhibited in comparison to their known F-BODIPY analogues 3a, 4a and 5a (cf.
View Article and Find Full Text PDFGlioblastoma (GBM) remains an orphan cancer disease with poor outcome. Novel treatment strategies are needed. Immunotherapy has several modes of action.
View Article and Find Full Text PDFPurpose: To assess the performance of a 2.5-minute multi-contrast brain MRI sequence (NeuroMix) in diagnosing acute cerebral infarctions.
Methods: Adult patients with a clinical suspicion of acute ischemic stroke were retrospectively included.