Comparative Side-Effects of Neurosurgical Treatment of Treatment-Resistant Depression.

Introduction: Treatment-resistant depression (TRD) is a condition in which patients suffering from depression no longer respond to common methods of treatment, such as anti-depressant medication. Neurosurgical procedures such as ablative surgery, deep brain stimulation, and vagus nerve stimulation have been used in efforts to overcome TRD.

Objectives: This review aims to provide an overview of the side effects of neurosurgery performed in clinical studies related to depression.

Time and dose selective glucose metabolism for glucose homeostasis and energy conversion in the liver.

Hepatic glucose metabolism serves dual purposes: maintaining glucose homeostasis and converting glucose into energy sources; however, the underlying mechanisms are unclear. We quantitatively measured liver metabolites, gene expression, and phosphorylated insulin signaling molecules in mice orally administered varying doses of glucose, and constructed a transomic network. Rapid phosphorylation of insulin signaling molecules in response to glucose intake was observed, in contrast to the more gradual changes in gene expression.

Effectiveness of 2-Terminal Perovskite/Perovskite/c-Si Triple-Junction Solar Cells: An Integrated Study with an Emphasis on Methylammonium Bismuth Iodide.

The growing interest in high-efficiency solar energy technologies has driven research on multijunction solar cells to flourish over the last several years. This study sheds light on the optical, structural, and morphological aspects of the (CHNH)BiI ((MA)BiI) film by fabricating and analyzing it experimentally. This thorough investigation lays the groundwork for more research into the film's possible uses in solar cell technology.