Publications by authors named "T So"
TNF receptor-associated factors (TRAFs) function as intracellular adaptor proteins utilized by members of the TNF receptor superfamily, such as CD40. Among the TRAF family proteins, TRAF5 has been identified as a potential regulator of CD40. However, it remains unclear whether TRAF5 regulates the generation of germinal center (GC) B cells and antigen-specific antibody production in the T-dependent (TD) immune response.
View Article and Find Full Text PDFMeigs syndrome after treatment for catamenial pneumothorax.
Gen Thorac Cardiovasc Surg Cases
November 2023
Article Synopsis
- Catamenial pneumothorax (CP) is a rare condition affecting women, characterized by a collapsed lung associated with menstrual cycles, while Meigs syndrome (MS) involves benign ovarian tumors causing pleural effusion and ascites, and its exact causes are not well understood.
- A 40-year-old Japanese woman was diagnosed with CP after experiencing dyspnea and undergoing surgery that revealed diaphragmatic foramens.
- Ten years later, the same patient presented with chest pain and imaging showed signs of MS, leading to surgery that resolved her symptoms, highlighting the rare occurrence of both conditions in one patient and suggesting links between them.
Background: Treatment response evaluated by tumour size change is an important indicator for outcome prediction. Advanced nasopharyngeal carcinoma (adNPC) grows irregularly, and so the unidimensional measurement may not be accurately applied to adNPC for outcome prediction. This study aimed to evaluate values of unidimensional and volumetric measurements for treatment response to induction chemotherapy (IC) for outcome prediction in adNPC and compared the values with that of RECIST 1.
View Article and Find Full Text PDFObjectives: To investigate the potential of T1rho, a new quantitative imaging sequence for cancer, for pre and early intra-treatment prediction of treatment response in nasopharyngeal carcinoma (NPC) and compare the results with those of diffusion-weighted imaging (DWI).
Materials And Methods: T1rho and DWI imaging of primary NPCs were performed pre- and early intra-treatment in 41 prospectively recruited patients. The mean preT1rho, preADC, intraT1rho, intraADC, and % changes in T1rho (ΔT1rho%) and ADC (ΔADC%) were compared between residual and non-residual groups based on biopsy in all patients after chemoradiotherapy (CRT) with (n = 29) or without (n = 12) induction chemotherapy (IC), and between responders and non-responders to IC in the subgroup who received IC, using Mann-Whitney U-test.