Imagine a world without cancer.

Background: Since the "War on Cancer" was declared in 1971, the United States alone has expended some $300 billion on research, with a heavy focus on the role of genomics in anticancer therapy. Voluminous data have been collected and analyzed. However, in hindsight, any achievements made have not been realized in clinical practice in terms of overall survival or quality of life extended.

Surgical treatment of Clostridium colitides.

Introduction: Infection with Clostridium difficile (CDI) is the most frequent cause of nosocomial diarrhoeas. Most cases are successfully treated by antibiotic therapy, but nearly 10% may progress to the fulminative form of this condition. The objective of the work is retrospective evaluation of the results of surgical treatment in patients with the fulminative form of Clostridium colitis with revealing of risk factors leading to serious post-operative morbidity and mortality.

[Preoperative radiotherapy in hypoxia in the complex treatment of the rectal carcinoma--long term results].

Introduction: The aim of this study was to evaluate long term results of patients with rectal carcinoma which were irradiated in hypoxic conditions.

Patients And Methods: Of all patients which were irradiated in hypoxic conditions in Masaryk Memorial institute, 93 patients were followed up longer time than five year.

Results: The most common surgical procedure was resection in 60%, overall five year survival was 73.

[Preoperative radiotherapy in hypoxia in the complex treatment of the rectal carcinoma--complications].

Introduction: Preoperative radiotherapy is considered to be the standard approach in the treatment of the rectal carcinoma. Acute hypoxia decreases partial pressure of oxygen in healthy tissues immediately, but in the tumor after 30 min of duration. There is a higher radioresistance of healthy tissues in this interval because of lower oxygenation compared with normooxic status and the tumor is still relatively good oxygenated.

Colon polyposis syndromes. Indications to surgery.

Familial polyposis syndromes create a group of hereditary syndromes of gastrointestinal tumours. We shall focus on those, touching mostly large bowels and need radical surgery.