International standards for conducting biomedical research with human participation.

Objective: Aim: To conduct a comprehensive analysis and systematization of international standards for biomedical research involving human participants, to identify their key principles and implementation mechanisms, as well as to evaluate their effectiveness in ensuring ethical and legal norms during such research..

Patients And Methods: Materials and Methods: This research employs a diverse array of scientific inquiry methods, encompassing both general scientific approaches and specialized techniques.

[The evaluation of concentration of certain NSAID in the procedure of screening medicinal and narcotic substances in blood].

We have undertaken the metrological assessment of the method for the quantitative determination of a number of non-steroidal anti-inflammatory drugs (NSAID) including ibuprofen, ketorolac, diclofenac, indomethacin, naproxen, and ketoprofen with the use of gas chromatography mass spectrometry in the model blood samples in the framework of the screening survey of medicinal and narcotic substances. The method was evaluated in terms of the following characteristics: specificity, linearity, correctness, precision (reproducibility), and intra-laboratory precision. The proposed method can be applied for the quantitative evaluation of indomethacin, ketoprofen, and naproxen content as well as for the preliminary quantitative determination of ibuprofen and diclofenac in the framework of the chemico-toxicological and forensic chemical analysis.

[The first experience in using elastography in combination with endobronchial ultrasonography for mediastinal pathology: Preliminary assessment of feasibility and comparison of characteristics via different approaches].

Objective: To preliminarily assess the feasibility of elastography in endobronchial ultrasonography and to compare characteristics via different accesses.

Material And Methods: The investigation enrolled 3 patients (malignant, benign mediastinal adenopathy, paratracheal tumor). Elastography was carried out using a Pentax EB-1970UK echobronchoscope with a Hitachi Noblus ultrasound scanner.

Endoscopic ultrasonography for intra-abdominal textiloma.

Introduction: The term textiloma is used to describe foreign body (swab) forgotten during surgery. We don't know any case of the description of endoscopic ultrasonography (EUS) for intra-abdominal textiloma.

Objectives: To determine the EUS capabilities in the topical diagnosis of intra-abdominal textiloma.

True and false splenic artery aneurysm on endoscopic ultrasonography: Two-case analysis.

Introduction: The etiology of true and false splenic artery aneurysm is different, but the differential X-ray contrast diagnosis could be difficult. Purpose - to detect endoscopic ultrasonography (EUS) diagnostic capability for false and true splenic artery aneurysm by considering two clinical cases: With suspected stomach and pancreatic lesions.

First Case: Patient, female, 50-year-old with suspected stomach lesion, complicated by gastric bleeding.