Publications by authors named "T Shimuzu"

Article Synopsis
  • HIV-associated lipodystrophy, linked to anti-retroviral therapy (ART), can lead to cardiovascular diseases and negatively impact the quality of life for HIV-infected individuals.
  • The study introduces a Pharmacological Lipid Index (PLI) to assess the risk of hyperlipidemia linked to various ART drugs, using lipid droplet staining and drug concentration signals.
  • Results show that early proteinase inhibitors and the drug d4T have low PLI/EC values, indicating a high risk of hyperlipidemia, while drugs with higher PLI/EC scores show fewer such issues, suggesting PLI/EC is a valuable risk estimation tool.
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Purpose: In current electrodiagnostic criteria for chronic inflammatory demyelinating polyneuropathy, the cutoff values of distal compound muscle action potential (DCMAP) duration are defined using electromyogram low-cut filter setting of 20 Hz. We aimed to assess effects of low-cut filter on DCMAP duration (10 vs. 20 Hz).

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A large-scale transcriptome database of rat liver (TG-GATEs) has been established by the Toxicogenomics Project in Japan. In the present study, we focused on 8 hepatotoxic compounds within TG-GATEs, i.e.

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Unlabelled: We evaluated the significance of the preoperative serum C-reactive protein (CRP) level as a prognostic indicator in patients with non-small cell lung cancer (NSCLC).

Patients And Methods: Two hundred and three patients who had undergone a curative resection of NSCLC were retrospectively reviewed.

Results: The proportion of the tumor size over 3 cm per patient in the CRP-positive group (> or =0.

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The purpose of this study was to explore the influence of age on regional cerebral blood flow (rCBF) patterns in patients with Alzheimer's disease (AD). Single photon emission computed tomography (SPECT) was performed in 79 patients with AD, including 31 younger and 48 older patients divided according to age at examination (<70 and > or = 70 years), and the SPECT data were analyzed using three-dimensional stereotactic surface projection. Although no significant differences in severity and duration of disease between the two groups were found, there were some differences in rCBF patterns.

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