Publications by authors named "T Shibuya"
Background: A serum biomarker for diagnosing ulcerative colitis (UC) remains to be established. Although we recently reported an anti-integrin αvβ6 antibody (V6 Ab) for diagnosing UC with high sensitivity and specificity, no large-scale validation study exists. This study aimed to validate the diagnostic value of V6 Ab for UC using a nationwide multicenter cohort study.
View Article and Find Full Text PDFHydroponics, despite its potential for efficient crop production, relies heavily on chemical fertilizers derived from nonrenewable resources and thus contributes to environmental burdens and unsustainable use of phosphorus. Integrating hydroponics into a circular phosphorus economy is crucial for mitigating these impacts. This study quantitatively assessed the capacity of filtrates from nitrified biogas digestate (f-NBD), a nutrient solution derived from organic waste, to replace phosphorus and nitrogen in hydroponic chemical nutrient solutions.
View Article and Find Full Text PDFBackground: Three Janus kinase (JAK) inhibitors are approved for ulcerative colitis (UC) in Japan.
Aim: To compare the real-world efficacy and safety of these three JAK inhibitors in UC.
Methods: This was a multicentre, retrospective study of patients with UC started on JAK inhibitors.
Article Synopsis
- Prebiotic synthesis of complex organic molecules has been difficult, but recent observations of liquid CO emissions in deep-sea environments suggest the existence of benthic CO pools.
- A new hypothesis proposes that a two-phase environment of supercritical CO (ScCO) and water can enhance the dehydration and condensation of organic compounds.
- Experiments demonstrated that this ScCO-water environment successfully produced various nucleoside monophosphates, indicating its potential to stimulate prebiotic nucleotide synthesis in extreme conditions, relevant both on Earth and in extraterrestrial ocean worlds.