Publications by authors named "T Shibutani"
Objectives: Brain perfusion single-photon emission computed tomography (SPECT) image quality varies depending on SPECT systems. This study aimed to evaluate the relationship between physical parameters and visual analysis for assessment of the brain SPECT image quality. We conducted our phantom study under various conditions in a multi-center and multi-vendor study.
View Article and Find Full Text PDFThis biomarker study explored HER2 expression levels and immune cell characteristics that may affect response to T-DXd using tumor tissue samples collected from clinical trial participants. The results suggest that HER2 expression levels and tumor characteristics before the initiation of T-DXd may correlate with the efficacy of the drug.
View Article and Find Full Text PDFBackground: Financial toxicity impacts the treatment choices, daily life, and health-related quality of life (HRQoL) of cancer patients. We investigated future variations in financial toxicity and HRQoL of patients with gynecologic cancer, evaluated using the COmprehensive Score for financial Toxicity (COST) questionnaire.
Methods: This multicenter study enrolled patients with gynecologic cancer incurring co-payments for anti-cancer drug treatment for over 2 months.
We evaluated the effect of different xSPECT Bone acquisition methods on image quality and quantitative accuracy. A mixed bone-equivalent solution set to 250 HU and Tc was filled with the SIM Bone phantom. The xSPECT Bone acquisitions were performed with the step and shoot (SS) mode and two continuous modes (continuous, continuous) of the times per view, and the total acquisition times were the same as the SS mode.
View Article and Find Full Text PDFArticle Synopsis
- - The study highlights the challenge of insufficient diagnostic tools for nuclear medicine imaging in newborns, particularly those with extremely low birth weight, and suggests investigating new technology to address this issue.
- - Researchers created a phantom model of a 500-g infant to test cardiac PET imaging with SiPM technology, assessing its ability to visualize a 3-mm myocardial defect using two different tracers (F-FDG and F-flurpiridaz).
- - Results showed that while SiPM PET could effectively image the heart, both tracers overestimated defect accumulation, with F-flurpiridaz providing better contrast, suggesting its preference for future studies if limited to one tracer.