Publications by authors named "T Shanmukha Babu"

Cisplatin and oxaliplatin are Pt(II) anticancer agents that are used to treat several cancers, usually in combination with other drugs. Their efficacy is diminished by dose-limiting peripheral neuropathy (PN) that affects ∼70% of patients. PN is caused by selective accumulation of the platinum drugs in the dorsal root ganglia (DRG), which overexpress transporters for cisplatin and oxaliplatin.

View Article and Find Full Text PDF

Background: Understanding protection against SARS-CoV-2 infection by vaccine and hybrid immunity is important for informing public health strategies as new variants emerge.

Methods: We analyzed data from three cohort studies spanning September 1, 2022-July 31, 2023, to estimate COVID-19 vaccine effectiveness (VE) against SARS-CoV-2 infection and symptomatic COVID-19 among adults with and without prior infection in the United States. Participants collected weekly nasal swabs, irrespective of symptoms, annual blood draws, and completed periodic surveys, which included vaccination status and prior infection history.

View Article and Find Full Text PDF
Article Synopsis
  • A study was conducted from September 2022 to April 2023 to evaluate how COVID-19 vaccines affect the risk of infection in children under 5 years old.
  • The results showed no significant difference in infection risk between vaccinated and unvaccinated children.
  • Although the vaccines are effective in preventing severe illness, they may not prevent the actual infection of the virus in young kids.
View Article and Find Full Text PDF
Article Synopsis
  • The paper investigates a new composite made from kenaf fiber, glass fiber, and graphene reinforced with epoxy, focusing on its water absorption and mechanical properties.
  • It highlights a gap in research regarding kenaf fibers combined with E-glass fibers and varying amounts of graphene (0.5% and 1.0%).
  • Results indicate that adding graphene enhances tensile strength, flexural strength, and water absorption, making these composites appealing for applications in industries like defense, biomedical, and automotive.
View Article and Find Full Text PDF