Publications by authors named "T Shaburishvili"

Article Synopsis
  • * The study included 51 patients and found a high safety rate, with 92.2% free from target lesion failure at 180 days and 90.2% at one year.
  • * The new DCB showed significantly better results in reducing in-stent late lumen loss compared to standard balloon angioplasty, indicating its superior efficacy for ISR treatment.
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Article Synopsis
  • This study evaluated the effectiveness and safety of a new procedure called splanchnic nerve ablation for managing fluid volume in patients with heart failure and preserved ejection fraction (HFpEF).* -
  • Conducted as a phase 2, double-blind, randomized trial involving 90 patients across 15 centers, the study compared the outcomes of the nerve ablation procedure to a sham control.* -
  • Results showed no significant differences in both the primary outcomes (reduction in pulmonary capillary wedge pressure) and safety events between the treatment and control groups, suggesting that the nerve ablation may not provide the expected benefits for these patients.*
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Aims: Loop diuretics may exacerbate cardiorenal syndrome (CRS) in heart failure (HF). Direct sodium removal (DSR) using the peritoneal membrane, in conjunction with complete diuretic withdrawal, may improve CRS and diuretic resistance.

Methods And Results: Patients with HF requiring high-dose loop diuretics were enrolled in two prospective, single-arm studies: RED DESERT (n = 8 euvolaemic patients), and SAHARA (n = 10 hypervolaemic patients).

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