Publications by authors named "T Schytte"
Response to commentary on "Cumulative rib fracture risk after stereotactic body radiotherapy in patients with localized non-small cell lung cancer" by Tugcu et al.
Radiother Oncol
January 2025
Aims: In patients with locally advanced non-small cell lung cancer (LA-NSCLC), curative-intent radiotherapy (RT) or chemoradiotherapy (CRT) is associated with considerable toxicity, and approximately half of the patients die within two years. A better understanding of early mortality is needed to improve patient selection and guide supportive interventions. In this population-based, nationwide cohort study, we investigated the incidence, temporal distribution, and risk factors of early mortality.
View Article and Find Full Text PDF. The apparent diffusion coefficient (ADC) extracted from diffusion-weighted magnetic resonance imaging (DWI) is a potential biomarker in radiotherapy (RT). DWI is often implemented with an echo-planar imaging (EPI) read-out due to speed, but unfortunately low geometric accuracy follows.
View Article and Find Full Text PDFArticle Synopsis
- - This study investigates the risk of rib fractures in patients with localized non-small cell lung cancer (NSCLC) following stereotactic body radiotherapy (SBRT), examining both patient-related and dosimetric factors.
- - Out of 602 patients analyzed, 19% experienced rib fractures, with significant risk factors including female gender, bone density, and specific dosimetric parameters like V20 and V30 to the rib.
- - The findings indicate that while 19% of patients developed rib fractures, dosimetric parameters were more influential in predicting this risk than patient-related factors, highlighting the importance of treatment planning in SBRT.