Publications by authors named "T Schindler"
Background: The emergence and spread of Extended-Spectrum Beta-Lactamase (ESBL)-producing Escherichia coli pose significant challenges for treatment of infections globally. This challenge is exacerbated in sub-Saharan African countries, where the prevalence of ESBL-producing E. coli is high.
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- Regulation of dopamine activity is crucial for treating conditions like schizophrenia, with LB-102 being a new dopamine D/5-HT inhibitor aimed at this purpose.
- The study measured how effectively LB-102 occupied dopamine receptors in healthy volunteers using PET scans at various doses, finding that 50 mg consistently provided the desired occupancy over 24 hours.
- Results indicated that while steady dosing led to consistent receptor occupancy, the relationship between receptor occupancy and plasma concentrations was different than usual, and LB-102 was safe and well-tolerated across all tested doses.
Background: Collaboration between registered dietitians and gastroenterologists has not been evaluated in cystic fibrosis (CF). We surveyed registered dietitians and gastroenterologists regarding the current participation of gastroenterologists in CF centers and identified possible areas to enhance partnership between the two disciplines.
Methods: An anonymous online survey was distributed targeting registered dietitians and gastroenterologists involved in CF care through three international listservs (CF Nutrition, CF DIGEST, and PEDGI) over a 6-week period.