Publications by authors named "T Schepens"

What's new in pediatric critical care?

Best Pract Res Clin Anaesthesiol

June 2024

Article Synopsis
  • Pediatric intensive care medicine is advancing quickly, with significant new research focused on improving care for children.
  • Enhancements in mechanical ventilation and hemodynamic support are leading to better treatment outcomes, particularly for conditions like ARDS and heart disease.
  • Updated guidelines for sedation and nutrition aim to reduce complications and improve recovery, especially in critically ill pediatric patients.
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This study aims to resolve the unmet need for ventilator surge capacity by developing a prototype device that can alter patient-specific flow in a shared ventilator setup. The device is designed to deliver a predictable tidal volume (VT), requiring minimal additional monitoring and workload. The prototyped device was tested in an in vitro bench setup for its performance against the intended use and design criteria.

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Article Synopsis
  • The study investigated sarcopenia (muscle loss) in COVID-19 patients in intensive care by using ultrasound to measure muscle properties over time.
  • Results showed that changes in muscle thickness of the diaphragm and quadriceps (rectus femoris) were important for patient survival, with stable thickness linked to better outcomes.
  • Notably, 31% of patients returned home without extra rehab, indicating significant challenges in recovery related to early muscle atrophy and strength decline.
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The respiratory syncytial virus (RSV) represents the leading cause of viral lower respiratory tract infections (LRTI) in children worldwide and is associated with significant morbidity and mortality rates. The clinical picture of an RSV infection differs substantially between patients, and the role of viral co-infections is poorly investigated. During two consecutive winter seasons from October 2018 until February 2020, we prospectively included children up to 2 years old presenting with an acute LRTI, both ambulatory and hospitalized.

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