Publications by authors named "T Sasajima"

It is a clear fact that many complications in surgical treatment, not just in cardiovascular surgery, are caused by things related to surgical techniques. In other words, postoperative problems are already determined by preoperative surgical management and intraoperative surgical operations. This describes strategies to avoid the surgical complications of distal bypass using the autogenous veins for each item.

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Article Synopsis
  • In Japan, a study was conducted on the safety and efficacy of ligelizumab, an anti-IgE monoclonal antibody, for treating chronic spontaneous urticaria (CSU) in patients who weren't responding well to H1-antihistamines.
  • The study, which included 66 adult participants, showed that while 80.3% experienced mild to moderate side effects, there were no severe adverse events or anaphylaxis, and only 6.1% stopped treatment due to side effects.
  • Significant improvements were noted: UAS7 scores improved quickly by Week 4 and continued to improve by Week 52, with 50% of patients achieving no symptoms, and a notable increase in quality of life
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Myelodysplastic neoplasms (MDS) are defined by cytopenia and morphologic dysplasia originating from clonal hematopoiesis. They are also frequently complicated with diseases caused by immune dysfunction, such as Behçet's disease (BD) and secondary pulmonary alveolar proteinosis (sPAP). MDS with both BD and sPAP is extremely rare, and their prognosis is poor.

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Castleman disease (CD) is a lymphoproliferative disorder that manifests as hypergammaglobulinemia and severe inflammation with multiorgan involvement. However, renal involvement has been infrequently described in CD. We present a case of a 63-year-old Japanese male patient with multicentric CD (MCD) in whom kidney involvement, including impaired renal function and massive proteinuria, is present.

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