Synthesis and Antifungal Activity of Fmoc-Protected 1,2,4-Triazolyl-α-Amino Acids and Their Dipeptides Against Species.

In recent years, fungal infections have emerged as a significant health concern across veterinary species, especially in livestock such as cattle, where fungal diseases can result in considerable economic losses, as well as in humans. In particular, species, notably and , are opportunistic pathogens that pose a threat to both animals and humans. This study focuses on the synthesis and antifungal evaluation of novel 9-fluorenylmethoxycarbonyl (Fmoc)-protected 1,2,4-triazolyl-α-amino acids and their dipeptides, designed to combat fungal pathogens.

Modeling, synthesis and in vitro testing of peptides based on unusual amino acids as potential antibacterial agents.

Currently non-protein amino acids and synthetic peptides are widely used as blocks in drug design. Many proteases are of great interest for pharmacology due to their key role in various pathologies. Bacterial collagenase (EC 3.

Visualization of magnetic domains by near-field scanning microwave microscope.

A near-field scanning microwave microscope (NSMM) system was used for the investigation of magnetic properties of a hard disk (HD) under an external magnetic field. To demonstrate local microwave characterization of magnetic domains by NSMM, we scanned the HD surface by measuring the microwave reflection coefficient S(11) of the NSMM at an operating frequency near 4.4GHz.