Publications by authors named "T Sameshima"

Article Synopsis
  • - The study aimed to compare neuronal injury biomarkers in cerebrospinal fluid of pediatric patients experiencing complex febrile seizures (CFS) versus those with infection-triggered acute encephalopathy (AE), specifically looking at the pathogenesis of AE with biphasic seizures.
  • - Researchers analyzed cerebrospinal fluid samples from 63 patients collected within 24 hours of neurological symptoms; results indicated significantly higher levels of the biomarkers S100B and GDF-15 in patients diagnosed with AESD and AE, respectively.
  • - The findings suggest that elevated S100B levels indicate active astrocyte involvement in AESD pathology, while increased GDF-15 points to a stronger defense response linked to more severe neurological injuries in infection-trigger
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Pediatric cavernous sinus meningiomas are rare. Herein, we present the case of a 5-year-old boy who presented with progressive left oculomotor nerve palsy. A head magnetic resonance imaging revealed a mass lesion in the left cavernous sinus, following which tumor resection was performed.

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Article Synopsis
  • PIVKA-II is a marker for vitamin K deficiency in newborns, and its occurrence in neonatal blood at birth and its relation to gestational age were studied in this analysis.
  • The analysis revealed that 42.8% of infants tested positive for PIVKA-II, with a significantly higher incidence in term infants (49.4%) compared to preterm infants (29.7%).
  • After five days post-birth, PIVKA-II levels decreased, likely due to vitamin K prophylaxis, and only one case of vitamin K deficiency bleeding was observed.
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Combined endoscopic transsphenoidal surgery and craniotomy may be useful for tumors extending into the suprasellar region or ventricles and for tumors extending simultaneously into the nasal sinuses and intracranial space. This method allows two surgeons to share the surgical field while compensating for each other's blind spots and allows for safe tumor removal by separating the normal structure from the tumor and protecting the normal structure. Simultaneous combined endoscopic transsphenoidal surgery and craniotomy require a lot of equipment; however, by devising the layout of the equipment in the operating room, the staff involved in the surgery can perform their roles more effectively.

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