Cisplatin (Cisp) is a potent cancer drug, but its use is limited by acute kidney injury (AKI). Autophagy, a process that removes damaged proteins and maintains cellular homeostasis, has been shown to alleviate Cisp-induced AKI. The balance between autophagy and apoptosis is crucial to kidney protection.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2024
Background: Hearing aids are the most common conventional devices used to manage sensorineural hearing loss. Although safe and reliable methods, Hearing aids have some minor or moderate side effects that may be inconvenient for those patients and may result in patient non-compliance or even abandonment of their usage. One of the most common is ear irritation and itching.
View Article and Find Full Text PDFBackground: Evaluation of the influence of the age of the patients upon the outcomes of liver resection (LR) for hepatocellular carcinoma (HCC).
Methods: HCC patients who underwent LR between 2010 and 2020 were analyzed. They were divided into 3 groups depending on the patient's age.
Background: Two intra-coronal preparation designs with varying extensions of cuspal coverage can perform differently regarding their fracture resistance against introral forces.
Methods: Two materials (IPS e-max CAD [EX], VITA ENAMIC [EN]), and two different preparation designs (EX-D1), (EX-D2), (EN-D1), and (EN-D2) were investigated to compare their fracture resistance. A total of 40 (n = 40) caries free human mandibular molars were used.