Elevation of serum carcinoembryonic antigen as a possible predictor of response to pulse methylprednisolone in acquired idiopathic generalized anhidrosis.

Background: Acquired idiopathic generalized anhidrosis (AIGA) is a rare disorder primarily observed in Asian populations, particularly in Japan. Although pulse methylprednisolone therapy is an effective treatment for AIGA, predictors of therapeutic response remain poorly defined.

Objectives: To identify factors that predict the efficacy of pulse methylprednisolone therapy in patients with AIGA.