The impact of a heart failure management protocol based on a hospital-community pharmacist collaboration.

Background: Heart failure has a high readmission rate, but interventions by multiple professionals are effective. Although there is growing interest in the management of heart failure by community pharmacists in Japan, no effective method has been developed. We created and verified the effectiveness of a novel heart failure management protocol that community pharmacists could utilize.

SARC-F questionnaire and its predictive value for mortality risk in hospitalized younger adults: A retrospective study.

Background: Sarcopenia is a progressive loss of skeletal muscle mass and strength that can also occur in younger adults. The validity of the SARC-F questionnaire in younger populations has not been extensively investigated.

Methods: A retrospective study was conducted using medical records of patients aged <65 years who were admitted to and discharged from a 900-bed university hospital between April 2019 and March 2021.

Sex-related differences in eating-related distress experienced by patients with advanced cancer.

Background: Sex-related differences in eating-related distress (ERD) experienced by cancer patients have not previously been clarified.

Methods: We conducted a multicenter survey among advanced cancer patients referred to palliative care. Data on patient characteristics were collected from the electronic medical records, and data on measurement outcomes were obtained from a questionnaire.

Targeting Heat Shock Transcription Factor 4 Enhances the Efficacy of Cabozantinib and Immune Checkpoint Inhibitors in Renal Cell Carcinoma.

Recently, immune checkpoint inhibitors (ICIs) and cabozantinib, a tyrosine kinase inhibitor (TKI), have been used to treat renal cell carcinoma (RCC); the combination of these agents has become a standard treatment for RCC. TKIs generally target vascular endothelial growth factor. However, cabozantinib is characterized by its targeting of MET.

Single-Use Flexible Bronchoscope in Facilitating Endobronchial Valve Treatment in Severe Emphysema.

Ensuring proper placement of one-way endobronchial valves is a vital step in achieving successful bronchoscopic lung volume reduction. The ability to navigate into sharply angled airways may be limited by the maximal flexion capability of bronchoscopes. We sometimes encounter difficult anatomical situations, causing a challenging, or sometimes even impossible placement of the EBV in the appropriate position due to steep bronchial bifurcation angles, particularly in the apical segments.