Publications by authors named "T SHODA"
Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a major complication of rheumatoid arthritis (RA), but effective treatment remains an unmet need in its management. Our aim was to evaluate the therapeutic efficacy of abatacept for RA-ILD. This observational retrospective study included patients with RA-ILD treated with abatacept between 2012 and 2021.
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- This study investigated clinical indicators that can help predict relapses in patients with interstitial lung disease (ILD) who have anti-aminoacyl-tRNA synthetase (ARS) antibodies, treated with prednisolone and calcineurin inhibitors.
- Fifty patients were monitored over a span of up to 4.8 years, where 38% experienced relapses, and researchers analyzed various factors to determine what might signal a relapse.
- Key findings showed that acute/subacute ILD, high serum levels of aldolase and surfactant protein-D, and low forced vital capacity percentages are significant risk factors, enabling earlier predictions and potentially better management of the condition.
Eosinophilic esophagitis (EoE) is a chronic, allergic inflammatory disease of the esophagus characterized by eosinophil accumulation and has a growing global prevalence. EoE significantly impairs quality of life and poses a substantial burden on healthcare resources. Currently, only two FDA-approved medications exist for EoE, highlighting the need for broader research into its management and prevention.
View Article and Find Full Text PDFBackground: A 6-food elimination diet in pediatric eosinophilic esophagitis (EoE) is difficult to implement and may negatively affect quality of life (QoL). Less restrictive elimination diets may balance QoL and efficacy.
Objective: We performed a multisite, randomized comparative efficacy trial of a 1-food (milk) elimination diet (1FED) versus 4-food (milk, egg, wheat, soy) elimination diet (4FED) in pediatric EoE.