The Effects of Percentage-Based, Rating of Perceived Exertion, Repetitions in Reserve, and Velocity-Based Training on Performance and Fatigue Responses.

Cowley, N, Nicholson, V, Timmins, R, Munteanu, G, Wood, T, García-Ramos, A, Owen, C, and Weakley, J. The effects of percentage-based, rating of perceived exertion, repetitions in reserve, and velocity-based training on performance and fatigue responses. J Strength Cond Res XX(X): 000-000, 2024-This study assessed the effects of percentage-based training (%1RM), rating of perceived exertion (RPE), repetitions in reserve (RIR), and velocity-based training (VBT) on (a) acute kinematic outputs, perceptions of effort, and changes in neuromuscular function during resistance training; and (b) neuromuscular fatigue and perceptions of soreness 24 hours after exercise.

Transforming Agricultural and Sulfur Waste into Fertilizer: Assessing the Short-Term Effects on Microbial Biodiversity via a Metagenomic Approach.

Fungi and soil bacteria are vital for organic matter decomposition and biogeochemical cycles, but excessive synthetic fertilizer use contributes to soil degradation and loss of biodiversity. Despite this, about 97% of soil microorganisms are unculturable, making them difficult to study. Metagenomics offers a solution, enabling the direct extraction of DNA from soil to uncover microbial diversity and functions.

Adolescent Idiopathic Scoliosis: Advances in Diagnosis and Management.

Purpose Of Review: Adolescent idiopathic scoliosis (AIS) is a disabling spinal pathology, with a significant morbidity if left untreated. This review investigates the recent advances in the diagnosis and management of AIS.

Recent Findings: Low radiation techniques have become a paramount focus in the management of patient's with AIS.

Improving debriefing practices for participants in social science experiments.

Social science experiments often expose participants to false, deceptive, or otherwise harmful content. In an effort to mitigate the effects of such content and to comply with regulatory standards, these studies usually conclude by "debriefing" participants about the content they encountered, on the assumption that doing so will eliminate the effects of exposure. We present evidence showing that this assumption is not always correct.

Functional assessment of IDUA variants of uncertain significance identified by newborn screening.

With the expansion of newborn screening efforts for MPS disorders, the number of identified variants of uncertain significance in IDUA continues to increase. To better define functional consequences of identified IDUA variants, we developed a HEK293-based expression platform that can be used to determine the relative specific activity of variant α-iduronidases by combining a fluorescence-based activity assay and semi-quantitative western blotting. We employed the current platform to characterize over thirty different IDUA variants, including known benign and pathogenic variants, as well as multiple variants of uncertain significance identified through newborn screening.