Adrenothyroid System - History of the Question. Structural Organization and Mechanism of Regulatory Functions.

The review considers the fundamental bases of the structural organization and mechanisms of the regulatory functions of the adrenothyroid system. Impairment of adaptation mechanisms caused by activation of uncontrolled processes of a stress reaction or weakening of controlled stress reaction is primarily associated with disorders in the adrenothyroid relationship and the development of adrenothyroid dysfunction syndrome.

[Enzymes of purine nucleotide metabolism in assessment of the functional competence of the immune system].

Blood lymphocyte activities of 5'-nucleotidases, adenosine deaminase and AMP deaminase have been investigated for evaluation of immune system state of albino rats under normal conditions, immobilization stress and effect of radiation. Stress-induced reactions were characterized by changes of activities of these enzymes. However the ratios of activities 5'- nucleotidase/AMP-deaminase (coefficient A) and adenosine-deaminase/AMP-deaminase (coefficient B) were even more informative than separate analysis of these enzymes.