Publications by authors named "T S Saraswathy Subramaniam"
Background: Point-of-care ultrasound (POCUS)/critical care ultrasound (CCU) use in medical and surgical intensive care units has surged over the last few decades. It is unclear if this has similarly translated in neurocritical care (NCC) units. We designed a survey to describe the current state of POCUS/CCU use and training among NCC providers.
View Article and Find Full Text PDFNeoadjuvant Chemotherapy and Transoral Robotic Surgery for Human Papillomavirus-Related Oropharyngeal Cancer.
JAMA Otolaryngol Head Neck Surg
December 2024
Article Synopsis
- - The study examines the effectiveness of a treatment strategy combining neoadjuvant chemotherapy (NECTORS) followed by surgery in preventing distant metastasis (DM) in patients with HPV-related oropharyngeal cancer, compared to standard care with concurrent chemoradiation (CCRT).
- - It includes 342 patients with advanced HPV-positive OPSCC, showing that NECTORS resulted in no cases of distant-only metastasis and fewer overall recurrences than CCRT.
- - The analysis considers various factors like age, sex, and cancer stage to assess DM-free survival rates, highlighting the potential benefits of NECTORS in reducing treatment-related toxicity.
: Osteoprotegerin (OPG) inhibits vascular calcification which is central to pathogenesis of arterial stiffness. However, it promotes inflammation by upregulating expression of vascular cell adhesion molecule-1(VCAM-1), thereby contributing to arterial stiffness. We investigated longitudinal association between OPG and arterial stiffness in type 2 diabetes (T2D), causality of the association and mediation by VCAM-1.
View Article and Find Full Text PDFArticle Synopsis
- About one in three Singaporeans faces a lifetime risk of developing diabetes mellitus (DM), often accompanied by other health issues that complicate treatment and management.
- The study involved 387 participants with self-reported Type 2 DM, analyzing the prevalence of DM complications, their sociodemographic factors, and the impact on health-related quality of life (HRQOL).
- Results showed that 31.6% of participants had DM-related complications, with younger age and higher education correlating with fewer complications; those with chronic conditions faced significant declines in physical and mental HRQOL.
Introduction: Postoperative nausea and vomiting (PONV) is a common side effect of all types of surgeries, especially so in bariatric surgery. Dexmedetomidine (DX) is an α2-agonist that may be useful as an adjunct prophylactic medication for PONV. This meta-analysis aims to evaluate the efficacy of DX in reducing the incidence and severity of PONV in laparoscopic bariatric surgeries.
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