Publications by authors named "T S Ramasubramanian"

Background & Aims: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Although biannual ultrasound surveillance with or without α-fetoprotein (AFP) testing is recommended for at-risk patients, sensitivity for early stage HCC, for which potentially curative treatments exist, is suboptimal. We conducted studies to establish the multitarget HCC blood test (mt-HBT) algorithm and cut-off values and to validate test performance in patients with chronic liver disease.

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  • Clothianidin is applied at planting in sugarcane to control termites, while organic manures are used to retain soil moisture.
  • The study measured how long clothianidin residues remained in sandy clay loam soil, finding they persisted for 90 days before dropping below detectable levels by 105 days.
  • Organic manures had a minimal effect on the persistence of clothianidin, with half-lives ranging from 21 to 24.8 days, raising concerns about medium-level risks to earthworms as residues dissipate.
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  • Termites are a significant pest for sugarcane, and bifenthrin is a pesticide used against them, applied during planting.
  • A study examined how long bifenthrin lasts in soil and sugarcane setts, finding it can persist for up to 75 days after treatment, with specific half-lives depending on the environment.
  • Photolysis isn't a significant factor in its breakdown since treated setts were shielded from sunlight; however, the pesticide may pose risks to earthworms due to its residue levels in the soil.
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Background & Aims: Hepatocellular carcinoma (HCC) can be treated effectively if detected at an early stage. Recommended surveillance strategies for at-risk patients include ultrasound with or without α-fetoprotein (AFP), but their sensitivity is suboptimal. We sought to develop a novel, blood-based biomarker panel with improved sensitivity for early-stage HCC detection.

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Thiamethoxam 75 SG has recently got registered for use against shoot borer and termites of sugarcane. It is the only neonicotinoid having label claim against both the major pests of sugarcane. The dissipation kinetics and environmental risk assessment of thiamethoxam 75 SG were studied in a typical tropical sugarcane crop ecosystem as detailed reports are lacking.

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