Publications by authors named "T S Perepanova"
Article Synopsis
- In the context of rising antibiotic resistance, managing infection sources and timely drainage removal is crucial.
- A clinical case is discussed involving a 42-year-old patient with various complications, including a urinary stent that led to an infection from pan-resistant Klebsiella pneumonia.
- The patient's severe condition, including septic shock and coagulation issues, was effectively treated with personalized local bacteriophage therapy.
Purpose: To provide a descriptive report of mortality and morbidity in the first 30 days of diagnosis of urosepsis. Secondary aim is to identify risk factors of unfavourable outcomes.
Methods: Prospective observational multicentre cohort study conducted from September 2014 to November 2018 in European hospitals.
The article is devoted to the stages of developing clinical recommendations on bacterial cystitis in accordance with the order of the Ministry of Health of Russia. Principles of evidence -based medicine (meta-analyses, systematic reviews and randomized clinical trials) are given. The Evidence Validity Level Assessment Scale (TDS) and Recommendation Credibility Level Assessment Scale (TDS) are given.
View Article and Find Full Text PDFThe negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010-2019.
World J Urol
September 2021
Purpose: To evaluate and report the complications, and to analyse antimicrobial stewardship aspects following prostate biopsies (P-Bx) based on the data from a 9-year global study.
Methods: The primary outcome was to compare complications after P-Bx between patients of two cohorts: 2010-2014 and 2016-2019. Primary outcomes included symptoms of lower and severe/systemic urinary tract infection (LUTIS and SUTIS, respectively), and positive urine culture.
A literature review dedicated to the problem of bacteriophage therapy for infectious and inflammatory diseases, including urological infections, is presented. Considering the growth of antibiotic resistance, the search for alternative treatments is relevant. Current data about bacteriophages and mechanism of their action, difference of virulent and temperate phages is given, as well as mechanisms of bacteria resistance to phages and ways of its overcoming.
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