[Prediction of the severity of damage and disruption of work ability in reaction of the body to alcohol load prior to radiation exposure in the superlethal range].

In experiments on 121 white non-linear rats, 44 Papio hamadryas and 29 Macaca fascicularis, animals' reactions on the alcohol impact (AI) and following exposure to supralethal doses were compared. The animals were intravenously injected with 5% ethanol in the glucose solution, 2.1 g/kg for rats and 0.

[Individual radioresistance and principles of its formation].

Individual variability of resistance to a broad range of ionizing radiation was analyzed. Individual radioresistance depends both on physical (radiation type, dose, and distribution along the body, dose rate) and biological (species, strain, sex, body mass of animal etc.) factors.

[A possibility to predict the severity of individual damage following the exposure to supralethal radiation dosage. Prediction of working capacity of irradiated rats and dogs by response to pre-exposure hypobaric load].

In experiments on rats and dogs exposed to radiation doses which cause intestinal and cerebral forms of radiation sickness, hypobaric hypoxia used as an unconventional test of animals' reactivity has enabled the relationship between reactivity and radiosensitivity to be established. Higher post-radiation efficiency is observed in animals with less pronounced changes during a barotest. The goodness of fit of experimental data to the expected result is up to 70%, rising if a set parameters for one index or the sum total of indices are used.

[A possibility to predict the severity of individual damage following the exposure to supralethal radiation dosage. Prediction of the clinical manifestation of radiation injury in laboratory animals by response to pre-exposure hypobaric hypoxia].

The experiments on rats, dogs and monkeys exposed to radiation doses which cause intestinal and cerebral forms of radiation sickness have shown that the severity of a clinical state can be predicted by cardiovascular and endocrine changes when a pre-exposure test with moderate hypobaric hypoxia is performed. The goodness of fit of experimental data to the exposed result is up to 60-80%, still rising if a set of indices of the neuroendocrine status is used.

[A possibility to predict the severity of individual damage following the exposure to supralethal radiation dosage. Prediction of working capacity of irradiated rats and dogs by response to pre-exposure physical load].

The experiments on rats and dogs exposed to radiation doses which cause intestinal and cerebral forms of radiation sickness have shown that, within the first 24 hours post-exposure, efficiency impairment can be predicted by changes in some indices of the cardiovascular and endocrine systems after physical load used as a non-radiation testing agent. The goodness of fit of experimental data to the expected result is up to 50-70%, still rising if a number of indices for different sections of the neuroendocrine system are used at a time.