[The Ca2(+)-binding capacity of the thrombocytes in rats with hydrocortisone-induced steroid hypertension].

The Ca(2+)-binding ability of the thrombocytes' membranes did not change within 30 min after administration of hydrocortisone when no significant changes of arterial pressure occur. In stable increase of arterial pressure evoked by thrice repeated administration of hydrocortisone, a redistribution of the intracellular Ca2+ occurs: its contents decreases at the external plasmatic membrane and increases in intracellular membranes. The hypertensive response seems to coincide with the redistribution.

[The compartmentalization of membrane-bound thrombocyte calcium in arterial hypertension].

High contents of Ca2+ was revealed in thrombocytes' intracellular compartments in patients with essential hypertension. In response to different stimuli, large amount of Ca2+ can be released in the platelets of the patients which makes a considerable contribution to generation of the Ca2+ signal and activation of thrombocytes in cardiovascular diseases.

[The membrane-bound calcium of the thrombocytes in essential hypertension].

The investigation was aimed at analyzing membrane-bound calcium in platelets of patients with essential hypertension (EH) and of healthy persons. 55 men were examined. Of these, 38 presented with EH and 17 were healthy.