Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides.

Commensal bacteria affect host health by producing various metabolites from dietary carbohydrates via bacterial glycometabolism; however, the underlying mechanism of action remains unclear. Here, we identified Streptococcus salivarius as a unique anti-obesity commensal bacterium. We found that S.

Determination of the Entire Existence Composition Range of CrMnFeCoNi High-Entropy Alloys Using Sintered Diffusion Multiple Method.

The sintered diffusion multiple (SDM) method, which has been developed in our research group, has been applied to determine the entire composition range of the CrMnFeCoNi high-entropy alloy stereoscopically and continuously over nearly the entire range. The samples were prepared by sintering mixed elemental powders and were annealed at 970 °C or 800 °C. Several hundreds of thousands of points were analyzed at random within the samples for chemical compositions using electron probe microanalysis.

Comparison of actionable alterations in cancers with kinase fusion, mutation, and copy number alteration.

Kinase-related gene fusion and point mutations play pivotal roles as drivers in cancer, necessitating optimized, targeted therapy against these alterations. The efficacy of molecularly targeted therapeutics varies depending on the specific alteration, with great success reported for such therapeutics in the treatment of cancer with kinase fusion proteins. However, the involvement of actionable alterations in solid tumors, especially regarding kinase fusions, remains unclear.

Relationship Between One-Leg Standing and Foot Sole Sensation Following Short-Term Immobilization of a Unilateral Lower Extremity.

Background: Several studies have suggested that approximately 10 hours of inactivity can reduce motor performance. Specifically, restricted lower limb movement may impair postural stability, subsequently increasing the incidence of falls. However, the relationship between postural sway and its related factors remains unclear.