Networks of pre-diagnostic circulating RNA in testicular germ cell tumour.

Testicular germ cell tumour (TGCT) is a malignancy with known inherited risk factors, affecting young men. We have previously identified several hundred differentially abundant circulating RNAs in pre-diagnostic serum from TGCT cases compared to healthy controls. In this study, we performed Weighted Gene Co-expression Network Analysis (WGCNA) on mRNA and miRNA data from these samples.

Therapists perspectives on the Early Intervention after Rape study: a qualitative process evaluation of a randomized controlled trial.

: Early interventions using trauma-focused cognitive behavioural therapy have the potential to alleviate post-traumatic stress symptoms in individuals who have experienced recent sexual assault. Specialized Sexual Assault Centers (SACs) in Norway offers psychosocial support, however, this support varies across SACs and its efficacy has not been researched. The Early Intervention after Rape (EIR) study is a multisite randomized controlled trial designed to assess the efficacy and effectiveness of training SAC nurses and social workers to deliver a modified version of prolonged exposure therapy shortly after rape.

Warning Signs, Monitoring Tools, and Actions Taken by World-Class Endurance Coaches in Cases of Underperformance.

Purpose: To describe warning signs, monitoring tools, and training- and non-training-related actions taken by world-class endurance coaches in cases of underperformance.

Methods: Twelve highly acclaimed male Norwegian coaches known for coaching world-class endurance athletes with a remarkable collection of over 350 Olympic, World, and European Championship medals-primarily with Norwegian athletes-participated in the study. Data collection and analyses followed a 3-step pragmatic qualitative study design, including an initial questionnaire, in-depth interviews, and structured negotiation between researchers and coaches.