Publications by authors named "T S Gadd"
Highly pathogenic avian influenza (HPAI) H5N1 is known for its virulence and zoonotic potential, infecting birds and mammals, thus raising public health concerns. Since 2021 its spread among birds has led to cross-species transmission causing epizootics among mammals, eventually impacting fur animal farms in Finland in 2023. To analyze the infectivity of the Finnish H5N1 isolates in human cells, representatives of diverse H5N1 isolates were selected based on the genetic differences, host animal species, and the year of occurrence.
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- Highly pathogenic avian influenza (HPAI A(H5N1)) caused high mortality rates among wild and domestic birds in Europe from 2020 to 2023, notably spreading to fur farms in Finland in July 2023.
- The virus was detected in animals like silver and blue foxes, minks, and raccoon dogs, showing severe health issues and mutations that may help it adapt to mammalian hosts.
- Close cooperation between animal and human health authorities was necessary to manage the outbreak and to address potential health impacts, as the virus was linked to mass bird die-offs and vulnerable farm biosecurity practices.
Post-vaccinal distemper-like disease in two dog litters with confirmed infection of vaccine virus strain.
Comp Immunol Microbiol Infect Dis
February 2024
Modified live canine distemper virus (CDV) vaccines are widely used and considered both safe and effective. Although there are occasional literature reports of suspected vaccine-induced disease, there are none where the vaccine strain has been identified in affected tissues. Here we describe two such cases in different litters.
View Article and Find Full Text PDFWe report cases of mammalian infection with highly pathogenic avian influenza (HPAI) virus A(H5N1) clade 2.3.4.
View Article and Find Full Text PDFSince mid-July 2023, an outbreak caused by highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.
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