Publications by authors named "T S David-West"

The immune status of 100 Nigerian children (ages 0-14) from a paediatric hospital in Ibadan, against poliovirus, after the administration of polyvalent oral poliovirus vaccine (types 1, 2 and 3) was determined using serum neutralisation test. High antibody titres were demonstrated in 78% of all the age groups tested. 57% of children under two years of age, 75% of those three to five years, and 100% of those above six years, had high poliovirus antibodies.

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Faecal samples from 84 children presenting with acute gastroenteritis at the University College Hospital, Ibadan, Nigeria and 28 from a non-diarrhoeal control group were tested for rotavirus by an ELISA. 18 cases (21%) and none of the controls were positive. Hospital in-patients had a higher percentage of positives (25%) than did out-patients (10%).

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During the years 1964 to 1970, 171 arboviruses of 15 different types were isolated from humans in Nigeria. Isolation rates were highest in 1969, and lowest in 1965 and 1967. Monthly arbovirus activity was highest in the rainy season months of June, July and August and lowest in the dry months of January and February.

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Concurrent and consecutive infection and immunisation with yellow fever virus and UGMP-359 virus was investigated in mice, using identical doses of both viruses. In double infection it was shown that both viruses could multiply independently of one another, when both were inoculated simultaneously by the intracerebral route. On the other hand, there was mutual exclusion between them when the inoculation of one antedated the other, by the same intracerebral route.

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