* Neurocognitive testing (NCT) revealed mild impairments in some patients, while brain imaging (BI) showed abnormalities in only 14.5% of cases, suggesting that the changes may not be directly linked to COVID-19 effects.
* Patients with severe CS were more likely to experience symptoms of depression, fatigue, and a lower quality of life, indicating a potential connection between cognitive symptoms and overall mental health issues among Post COVID-19 patients.
Bullous pemphigoid (BP) and pemphigus vulgaris (PV) are autoimmune skin diseases, with BP characterized by intense itching which may involve the cytokine IL-31.
Research compared the expression of IL-31 and its receptor IL-31RA in skin samples from BP and PV patients, revealing significantly higher levels in BP, especially in advanced lesions.
The findings suggest that IL-31/IL-31RA signaling could contribute to the difference in pruritus and inflammation between BP and PV, indicating potential for targeted therapies in BP patients.