The role of interventional radiology in the management of intra- and extra-peritoneal leakage in patients who have undergone continent urinary diversion.

Purpose: To assess how radiologic intervention altered the hospital course of patients undergoing continent urinary diversion.

Methods: Thirty-seven consecutive patients with bladder cancer invading the muscular layer were treated with total cystectomy and construction of a continent urinary reservoir. Eleven of 37 patients suffered early and late anastomotic leakage; six had prolonged extraperitoneal leakage at the urethroenteric anastomosis, three had prolonged intraperitoneal pouch leaks, and two had delayed ureteroenteric leaks.

Lack of interaction between magnetic resonance imaging and the copper-T380A IUD.

To determine if the CuT380A (ParaGard) IUD is affected by magnetic resonance imaging (MRI), in vitro studies utilizing a CuT380A IUD (ParaGard), a copper-bearing IUD, and a Signa 1.5T HR system were used to evaluate whether the dynamic magnetic forces generated by the MRI resulted in movement, torque, or heat when the IUD was exposed to the magnetic field generated by the MRI. There was no deflection, turning motion (torque), or temperature change when the IUD was exposed to a magnetic field.

Selective blockade of cholecystokinin type B receptors with L-365,260 does not impair gallbladder contraction in normal humans.

Objectives: To evaluate the effect of selective blockade of type B cholecystokinin receptors on gall bladder contraction in normal humans and to compare methods for quantitative analysis of gall bladder contraction.

Methods: L-365,260, a novel, nonpeptide cholecystokinin antagonist shown to be selective for type B cholecystokinin receptors, was administered every 6 h over a 5-7 day period. Plasma levels of L-365,260 were determined by high pressure liquid chromatography.