WEBA dataset as the Reflection of Work content effect on Workload perception in Real life Working conditions.

The effect of work content on workload, stress, and performance was not well addressed in the literature, due to the lack of comprehensive conceptualization, problem definition, and relevant dataset. The gap between laboratory-simulated studies and real-life working conditions delays the generalization, hindering the development of performance management and monitoring tools. Contributing to this topic, a data collection effort is organized, which considers unique work conditions and work content factors of a coffee shop, to conceptualize scenarios that better highlight their effect on human performance, thus creating the Work content Effect on BAristas (WEBA) dataset.

Evaluating Patient Participation in Clinical Trials for CLL and SLE in Germany-A Mixed-Methods Study on Enrollment Potential Based on Claims Data.

In recent years, the pharmaceutical industry in Germany has faced a significant decline in the number of clinical trials conducted. This study evaluates patient participation in clinical trials for oncology and chronic diseases in Germany, integrating quantitative and qualitative research. Data from the Institute for Applied Health Research Berlin (InGef (Institut für angewandte Gesundheitsforschung, Berlin, Germany)), covering about 88% of the German population, and expert interviews were used.

Dinuclear Dysprosium Compounds: The Importance of Rigid Bridges.

We report the synthesis, structures and magnetic behaviour of two isostructural dinuclear Dy complexes where the metal ions of a previously reported monomeric building block are connected by a peroxide (O ) or a pair of fluoride (2×F) bridges. The nature of the bridge determines the distance between the metal ion dipoles leading to a dipolar coupling in the peroxido bridged compound of only ca. 70 % of that in the bis-fluorido bridged dimer.

Infection length and host environment influence on Plasmodium falciparum dry season reservoir.

Persistence of malaria parasites in asymptomatic hosts is crucial in areas of seasonally-interrupted transmission, where P. falciparum bridges wet seasons months apart. During the dry season, infected erythrocytes exhibit extended circulation with reduced cytoadherence, increasing the risk of splenic clearance of infected cells and hindering parasitaemia increase.

CRKL Enhances YAP Signaling through Binding and JNK/JUN Pathway Activation in Liver Cancer.

The Hippo pathway transducers yes-associated protein (YAP) and WW-domain containing transcription regulator 1 (WWTR1/TAZ) are key regulators of liver tumorigenesis, promoting tumor formation and progression. Although the first inhibitors are in clinical trials, targeting the relevant upstream regulators of YAP/TAZ activity could prove equally beneficial. To identify regulators of YAP/TAZ activity in hepatocarcinoma (HCC) cells, we carried out a proximity labelling approach (BioID) coupled with mass spectrometry.