Publications by authors named "T Reidy"
Article Synopsis
- Phage therapy uses lytic bacteriophages to combat multidrug-resistant bacterial infections, showing significant success in Eastern Europe but limited research on its effects on human hosts.
- Researchers investigated how lytic phages interact with airway epithelial cells, especially from a cystic fibrosis patient, revealing that these interactions depend on the properties of the phage and the environment.
- The airway epithelium does not effectively internalize phages but responds to them by altering gene expression and releasing certain cytokines, suggesting that both phage and host factors should be considered for effective phage therapy.
Article Synopsis
- Phage therapy utilizes lytic bacteriophages to combat multidrug resistant infections, showing promising results in Eastern Europe but lacking extensive data on human interactions.
- The study investigates how lytic phages interact with airway epithelial cells, finding that these interactions vary based on phage properties and the microenvironment.
- Results indicate that airway epithelial cells change their functions in response to phage exposure, which could influence the effectiveness of phage therapy in respiratory infections.
The highly conserved HEATR5 proteins are best known for their roles in membrane traffic mediated by the adaptor protein complex-1 (AP1). HEATR5 proteins rely on fast-evolving cofactors to bind to AP1. However, how HEATR5 proteins interact with these cofactors is unknown.
View Article and Find Full Text PDFConstraint induced movement therapy is an established, evidence-based intervention for children with hemiplegia. This case series describes the feasibility and clinical opportunities of using a hybrid telehealth and onsite model to deliver pediatric constraint induced movement therapy during the COVID-19 pandemic. These cases support that a hybrid model had a similar effect on upper extremity improvement compared to a traditional, in-person model and may be an option when access to in-person care is not available.
View Article and Find Full Text PDFThe highly conserved HEATR5 proteins are best known for their roles in membrane traffic mediated by the adaptor protein complex-1 (AP1). HEATR5 proteins rely on fast-evolving co-factors to bind to AP1. However, how HEATR5 proteins interact with these co-factors is unknown.
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