Publications by authors named "T Rathod-Mistry"
Article Synopsis
- The study aimed to find out if there is a link between newly diagnosed frozen shoulder and later development of type 2 diabetes among adults in primary care in the UK.
- Researchers used a matched cohort design with over 31,000 patients each for those with frozen shoulder and without, while excluding those with prior diabetes.
- Results indicated that individuals with frozen shoulder had a significantly higher likelihood of being diagnosed with type 2 diabetes, suggesting the need for further investigation into screening practices for patients with frozen shoulder.
Article Synopsis
- - Evidence on osteoporosis treatments like denosumab and oral bisphosphonates shows variation in effectiveness due to differing populations, clinical practices, and study methodologies, which can affect treatment outcome comparisons.
- - This study analyzed 280,288 women over 50, comparing denosumab and oral bisphosphonates by using propensity score techniques to ensure the treatment groups were comparable before estimating treatment effects.
- - Results indicated that achieving balance in observed covariates was generally successful after applying propensity score methods, but some residual confounding was still present, depending on the databases used and analysis methods applied.
Background: Although vaccines have proved effective to prevent severe COVID-19, their effect on preventing long-term symptoms is not yet fully understood. We aimed to evaluate the overall effect of vaccination to prevent long COVID symptoms and assess comparative effectiveness of the most used vaccines (ChAdOx1 and BNT162b2).
Methods: We conducted a staggered cohort study using primary care records from the UK (Clinical Practice Research Datalink [CPRD] GOLD and AURUM), Catalonia, Spain (Information System for Research in Primary Care [SIDIAP]), and national health insurance claims from Estonia (CORIVA database).
Background: There are scarce data on best practices to control for confounding in observational studies assessing vaccine effectiveness to prevent COVID-19. We compared the performance of three well-established methods [overlap weighting, inverse probability treatment weighting and propensity score (PS) matching] to minimize confounding when comparing vaccinated and unvaccinated people. Subsequently, we conducted a target trial emulation to study the ability of these methods to replicate COVID-19 vaccine trials.
View Article and Find Full Text PDFObjective: To evaluate bias and precision of exposure-outcome effect estimates from three control sampling strategies in a case-crossover study.
Methods: Online case-crossover study investigating eight physical activity-related triggers for acute flares in knee osteoarthritis. Exposures were measured in hazard periods (≤24 hours before self-declared flare onset).