Publications by authors named "T Ramires"
A green method for anthocyanin extraction from Clitoria ternatea flowers cultivated in southern Brazil: Characterization, in vivo toxicity, and biological activity.
Glória Caroline Paz Gonçalves Alexandra Lizandra Gomes Rosas Rafael Carneiro de Sousa Thaís Regina Rodrigues Vieira Thamyres César de Albuquerque Sousa Tassiana Ramires
Food Chem
March 2024
This study aimed to develop a green method to obtain an anthocyanin-rich edible extract of Clitoria ternatea flowers grown in southern Brazil. The extract was characterized by UHPLC-MS and analyzed for toxicological potential in an in vivo model, total phenolic content, and biological activities. By using a 2 multivariate design to study the effects of temperature, acidified solvent, and time on the total anthocyanin content (487.
View Article and Find Full Text PDFArticle Synopsis
- This study used a label-free proteomics method to identify proteins in Campylobacter jejuni that respond to different pH levels, focusing on the reference strain NCTC 11168.
- Researchers grew the bacteria at normal pH levels (5.8, 7.0, and 8.0) and exposed it to a lower pH (4.0) shock, finding specific proteins that increased in abundance under acidic conditions even without activation from acid shock.
- The results indicate that C. jejuni adjusts its respiration and metabolism in response to pH changes, enhancing growth and energy conservation, which contributes to its competitiveness and overall fitness.
Article Synopsis
- The study aimed to compare COVID-19 patient characteristics, clinical management, and outcomes during the peak (weeks 10-16) and plateau (weeks 17-34) phases of the first pandemic wave in Portugal.
- A total of 541 adult patients, mostly male with a median age of 65, were analyzed, showing no significant differences in age, initial health scores, and 28-day mortality between the two periods.
- Key findings indicated fewer comorbidities, higher use of certain treatments (like vasopressors and invasive ventilation) during the peak, whereas the plateau saw increased use of different therapies like remdesivir and corticosteroids and shorter ICU stays.
Article Synopsis
- * Results showed that isolates were categorized into two main lineages, with lineage I displaying higher invasion capabilities in human cells and expressing a specific virulence factor called InlA.
- * isolates from lineage II exhibited lower invasion rates due to a lack of InlA expression or mutations that caused malfunction, indicating differences in virulence potential linked to the isolates' genetic backgrounds.