Publications by authors named "T Rajagopal"

Article Synopsis
  • * SNPs are prevalent in the population and have a significant role in sporadic ovarian cancers, emphasizing the importance of understanding their genetic basis for improving molecular diagnostics and developing personalized treatments.
  • * This review focuses on the impact of SNPs in critical caretaker genes responsible for genomic integrity and discusses the challenges of SNP-based research, highlighting the most studied pathways (DDR and HRR) while noting that other relevant pathways are underexplored.
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Pleural effusion is a common problem in our country, and most of these patients need invasive tests as they can't be evaluated by blood tests alone. The simplest of them is diagnostic pleural aspiration, and diagnostic techniques such as medical thoracoscopy are being performed more frequently than ever before. However, most physicians in India treat pleural effusion empirically, leading to delays in diagnosis, misdiagnosis and complications from wrong treatments.

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Paget disease of the breast is a rare breast cancer that accounts for 1-3% of all new presentations of breast cancer. It is characterized by an eczematous and ulcerative lesion of the nipple that may extend to the areola. Nearly 90% of cases are associated with underlying breast cancer.

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Spondylodiscitis is often diagnosed late in its course because its symptoms are vague. The incidence in adults increases with age, being seen most commonly in men in their 50s and 60s, so the presence of other medical conditions or infections can make it more difficult to identify spondylodiscitis. Diagnosis is made based on clinical suspicion, raised levels of inflammatory markers, a positive blood or tissue biopsy culture and radiological findings.

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