Publications by authors named "T Radulesco"
Impact of neck dissection in cN0 patients undergoing primary or salvage total laryngectomy.
Eur Arch Otorhinolaryngol
December 2024
Introduction: It is debatable whether neck dissection is necessary in patients with advanced laryngeal carcinoma who are clinically node-negative (cN0). We assessed the effect of neck dissection on overall survival in patients with cN0 undergoing primary or salvage laryngectomy.
Materials And Methods: A retrospective evaluation of cN0 patients who underwent primary or salvage total/pharyngolaryngectomy at a French tertiary facility in 2008-2018, with or without neck dissection, was carried out.
Differential Nasal Recolonization and Microbial Profiles in Chronic Rhinosinusitis With Nasal Polyps Patients After Endoscopic Sinus Surgery or Dupilumab Treatment: A Prospective Observational Study.
Clin Otolaryngol
October 2024
Introduction: The role of microbial profiles in Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) pathogenesis is increasingly recognised, with microbial imbalances perpetuating inflammation. We performed this study to associate the different nasal microbiological profile changes with the response to surgical or monoclonal treatment.
Methods: This prospective observational study evaluated changes in the nasal microbial profiles of 44 patients (22 dupilumab, 22 surgery) over 6 months.
Objective: To evaluate the efficacy of sound stimulation for enhancing drug distribution in the cochlea's perilymph, crucial for treating one of the most inaccessible organs and a major disability factor worldwide.
Design: A systematic scoping review following PRISMA guidelines was conducted, analysing studies on cochlear fluid dynamics influenced by sound stimulation. Data were collected from PubMed and Google Scholar using both MeSH and non-MeSH terms, with exclusions for unrelated topics.
Article Synopsis
- - Young European otolaryngologists (OTOs) were surveyed about their views on transoral robotic surgery (TORS), revealing a 26% response rate from participants.
- - Key barriers to TORS adoption included robot availability (73%), high costs (69%), and insufficient training (37%), while the main advantages were better surgical visibility (64%), reduced hospital stays (62%), and improved post-op outcomes (61%).
- - Despite these challenges, 67% of TORS practitioners felt adequately trained, and there was an overall positive perception of TORS among young OTOs, especially for specific cancer types and conditions.
Purpose: A hypometabolic profile involving the limbic areas, brainstem and cerebellum has been identified in long COVID patients using [F]fluorodeoxyglucose (FDG)-PET. This study was conducted to evaluate possible recovery of brain metabolism during the follow-up of patients with prolonged symptoms.
Methods: Fifty-six adults with long COVID who underwent two brain [F]FDG-PET scans in our department between May 2020 and October 2022 were retrospectively analysed, and compared to 51 healthy subjects.