Publications by authors named "T R Witt"
The Southern Plains (SP) is one of 18 Long-Term Agroecosystem Research network sites that combine strategic research projects with common measurements across multiple agroecosystems. Projects at the SP site focus on the use of indicator measurements to aid in assessment of land and nutrient management's impact on soil health, water quality, carbon and water balances, and forage biomass-quality in diversified, adaptive crop-livestock systems designed to overcome shifts in natural resources and climate. The prevailing treatment is tilled winter wheat (Triticum aestivum L.
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- The study investigates the long-term changes in local field potentials (LFPs) in patients with Parkinson's disease who are undergoing deep brain stimulation (STN-DBS), which has previously been less analyzed over time.
- A group of 22 patients underwent LFP recordings during three clinic visits without stimulation, revealing an increase in certain oscillatory activities (specifically low-beta, high-beta, and gamma band power) over time, while the primary peak amplitude remained consistent.
- The findings indicate that LFPs can be reliably measured across multiple clinical encounters, offering valuable information about their evolution in Parkinson's disease patients receiving STN-DBS treatment.*
Background: The purpose of this study was to investigate a therapeutic approach targeting the inflammatory response and consequent remodeling from ischemic myocardial injury.
Methods And Results: Coronary thrombus aspirates were collected from patients at the time of ST-segment-elevation myocardial infarction and subjected to array-based proteome analysis. Clinically indistinguishable at myocardial infarction (MI), patients were stratified into vulnerable and resilient on the basis of 1-year left ventricular ejection fraction and death.
The purpose of this study was to evaluate the biodistribution of a platelet-derived exosome product (PEP), previously shown to promote regeneration in the setting of wound healing, in a porcine model delivered through various approaches. Exosomes were labeled with DiR far-red lipophilic dye to track and quantify exosomes in tissue, following delivery via intravenous, pulmonary artery balloon catheter, or nebulization in sus scrofa domestic pigs. Following euthanasia, far-red dye was detected by Xenogen IVUS imaging, while exosomal protein CD63 was detected by Western blot and immunohistochemistry.
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