Treatment of anterior rim fractures of the distal radius with an anterior rim plate: A retrospective study.

Treatment of distal radial fractures that include small anterior rim fragments can be difficult. We retrospectively reviewed 19 patients in whom an anterior rim plate with locking screws was used. After a median follow-up of 18 months (range 6-32; interquartile range (IQR) 14, 26), the median wrist flexion and extension arc was 70° (range 50-80; IQR 60, 70), the median grip strength was 80% of the contralateral side (range 52-104; IQR 77, 88), the median visual analogue scale score for pain was 0 (range 0-5; IQR 0, 1), the median disabilities of the arm, shoulder and hand score was 2 (range 0-59; IQR 0, 11) and the median modified Mayo wrist score was 80 (range 35-100; IQR 75, 85).

Metabolic dysfunction-associated steatotic liver disease is associated with increased risks of heart failure.

Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD), defined by steatotic liver disease (SLD) and cardiometabolic factors, is increasing in prevalence, but its association with heart failure (HF) is unclear.

Methods And Results: Patients with SLD without a history of HF from 2006 to 2021 were retrospectively included and were classified into MASLD and non-MASLD groups that were followed longitudinally. The primary outcome was the new development of HF, which was sub-classified by echocardiography.

Indocyanine green-mediated photothermal release of lidocaine from genipin-crosslinked gelatin hydrogel in nerve block.

Local anesthetic (LA)-induced peripheral nerve block (PNB) is an important part of multimodal analgesia to reduce postoperative pain, accelerate postoperative recovery, and improve clinical prognosis. The duration of LA depends on anesthetics, and the repeated nerve positioning, puncture injection or indwelling catheter is often required to prolong the effect of PNB. In this study, the genipin, was used to crosslink gelatin-based hydrogel, and then co-loaded with indocyanine green (ICG) and lidocaine as an LA-controlled release system (ICG@Lido/Gel and ICG@Lido/gGel).

Developing a Serum-Free and Cytokine-Optimizing Induction Medium to Increase the Production of CD14CD16 and CD14CD16 Monocytes from Human CD133 Hematopoietic Stem and Progenitor Cells.

Immunotherapy utilizes immune cells to target cancer and improves treatment outcomes with few side effects. Despite the effectiveness of immunotherapy, the limited availability of monocytes, which are essential for the differentiation of antigen-presenting cells, remains a major challenge. In this study, we developed a technique for inducing monocytes from hematopoietic stem and progenitor cells by using a serum-free (SF) medium supplemented with optimal concentrations of serum substitutes and cytokines.

Radiological Sublingual Space Invasion in Tongue Squamous Cell Carcinoma: Clinicopathological Associations and Impact on Survival.

Objectives: We investigate if sublingual space invasion (SLI) determined on magnetic resonance imaging confers differences in clinicopathological manifestations and treatment outcomes of oral tongue squamous cell carcinoma (OTSCC).

Study Design: Retrospective cohort study.

Setting: Tertiary Academic Medical Center.