Publications by authors named "T R Rambo"

Article Synopsis
  • - A new method for portable near-infrared (NIR) fluorescence microscopy is presented, designed to improve imaging of biological samples using the NIR-II window.
  • - The integration of a superconducting nanowire single-photon detector (SNSPD) enhances the detection efficiency of the fluorescent dye indocyanine green (ICG), allowing for better imaging quality.
  • - This technique yields high-resolution images and a better signal-to-noise ratio, which could significantly benefit future clinical studies in fluorescence microscopy.
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Introduction: Low back pain can be defined as pain and/or discomfort between the coastal margins of the lowest rib and the gluteal fold, and it can cause motor dysfunction, loss of productivity, and changes in job function. There is a greater number of nursing professionals in hospital environments, and, regardless of their numerical contingent, they have the highest percentage of absenteeism due to this condition.

Objectives: To evaluate the association between perception of low back pain and occupational stress in hospital nursing professionals.

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Mixed human deoxyribonucleic acid (DNA) samples present one of the most challenging pieces of evidence that a forensic analyst can encounter. When multiple contributors, stochastic amplification, and allele drop-out further complicate the mixture profile, interpretation by hand becomes unreliable and statistical analysis problematic. Probabilistic genotyping software has provided a tool to address complex mixture interpretation and provide likelihood ratios for defined sets of propositions.

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Recently proposed time-gated diffuse correlation spectroscopy (TG-DCS) has significant advantages compared to conventional continuous wave (CW)-DCS, but it is still in an early stage and clinical capability has yet to be established. The main challenge for TG-DCS is the lower signal-to-noise ratio (SNR) when gating for the deeper traveling late photons. Longer wavelengths, such as 1064 nm have a smaller effective attenuation coefficient and a higher power threshold in humans, which significantly increases the SNR.

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Survivors of severe brain injury may require care in a neurointensive care unit (neuro-ICU), where the brain is vulnerable to secondary brain injury. Thus, there is a need for noninvasive, bedside, continuous cerebral blood flow monitoring approaches in the neuro-ICU. Our goal is to address this need through combined measurements of EEG and functional optical spectroscopy (EEG-Optical) instrumentation and analysis to provide a complementary fusion of data about brain activity and function.

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