[Dynamics of bacterial population waves in relation to the function of chemotaxis response].

The time of formation and rate of bacterial population waves as a function of substrate concentration has been investigated. It was shown both theoretically and in experiment that the time of wave formation increases with substrate concentration. At the same time, the rate of wave propagation decreases at relatively high substrate concentrations.

[Regulation of promoter activity through electrostatic interactions with RNA-polymerase].

Electrostatic profiles for sigma70-specific promoters of T4 bacteriophage and four consensus-like synthetic promoters have been calculated. It was shown that the promoters can be classified according to the presence of some specific electrostatic elements located in the far upstream region of their DNAs. A correlation between the electrostatic elements specific for promoters and their functional behaviour was established.

[Characteristics of electrostatic interaction of Escherichia coli RNA polymerase with promoters of T4 phage DNA].

A comparative analysis of electrostatic potential distribution for "early" T4 phage promoters was undertaken. The data obtained indicate that there are some particular elements in the patterns of electrostatic potential distribution of promoter DNA specific for promoter groups differing by their functional response to ADP-ribosylation of the alpha-subunit as well as to rpoB403- or rpoB409 mutationals of the beta-subunit of RNA-polymerase.