Publications by authors named "T R Crawshaw"

Spotty liver disease (SLD) is a bacterial disease of chicken, causing mortalities and reduction in egg production, hence, contributing to economic loss in the poultry industry. The causative agent of SLD has only recently been identified as a novel Campylobacter species, Campylobacter hepaticus. Specific primers were designed from the hsp60 gene of Campylobacter hepaticus and PCR followed by high-resolution melt curve analysis was optimised to detect and differentiate three species of Campylobacter (Campylobacter coli, Campylobacter jejuni and Campylobacter hepaticus).

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Article Synopsis
  • - In October 2019, an investigation into a free-range chicken flock in New Zealand revealed an outbreak of spotty liver disease, with post-mortem examinations showing liver lesions in 5 out of 8 hens.
  • - Histopathological analysis indicated severe liver damage and inflammation in the affected hens, and bile samples tested positive for a specific bacteria linked to the disease.
  • - Genome sequencing and phylogenetic analysis demonstrated that the outbreak strains were closely related to those from Australia, marking the first confirmed case of this disease in New Zealand's poultry, suggesting it should be considered in diagnoses of hen mortality.
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In 2015, a novel thermophilic Campylobacter was isolated from cases of spotty liver disease in laying hens in the UK. In 2016, it was isolated from laying hens in Australia where it was formally named Campylobacter hepaticus and confirmed as the cause of spotty liver disease. It has also been isolated from laying hens in America.

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Case History: A group of 39, 19-22-month-old Friesian bulls were administered an ivermectin/closantel anthelmintic via intended S/C injection in the ischiorectal fossa on 15 June 2017 (Day 0). Over the next 50 days, 22 affected bulls presented various degrees of anorexia, abdominal pain and urine dribbling. Seventeen bulls were examined by transrectal ultrasonography which revealed urinary bladder distension in all 17, and peritoneal fluid accumulation in some.

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