Publications by authors named "T R Brito"
Article Synopsis
- - The study investigates the role of Piwi proteins and piRNAs in protecting the genome of
- Rhodnius prolixus
- , a hemipteran insect known to transmit Chagas disease, from DNA damage caused by horizontally transferred transposable elements (HTTs) acquired from its diet.
- - By using SmallRNA-Seq and RNA-Seq techniques, researchers quantified piRNA features and gene expression levels, revealing that piRNA production peaks during embryogenesis, correlating with reduced expression of HTTs and resident transposable elements.
- - The findings highlight that while resident transposable element piRNAs engage in a typical ping-pong amplification mechanism, the response to HTTs is different, suggesting unique biogenesis and functional pathways for pi
Objective: To identify factors associated with poor sleep quality in elderly dependent individuals in social vulnerability.
Method: Cross-sectional study with 59 elderly dependent individuals assisted by Family Health Units in São Carlos/SP. The following tools were used: Katz Index, Lawton and Brody Scale, Pittsburgh Sleep Quality Index, Addenbrooke's Cognitive Examination Revised, Fried's Frailty Phenotype, Geriatric Depression Scale (15 items), Perceived Stress Scale, Family APGAR, Social Support Scale from the Medical Outcomes Study, and World Health Organization Quality of Life, abbreviated and "old" versions.
Article Synopsis
- Five new lignanamides and ten known amides were extracted from the roots' chloroform extract, with new compounds identified through NMR and mass spectrometry.
- The absolute configuration of one compound was determined using ECD experiments and quantum mechanical calculations.
- The anti-inflammatory effects of these compounds were tested on macrophages, showing that all reduced nitric oxide levels, while one compound did not significantly affect IL-10 levels, indicating potential anti-inflammatory properties.
Association between low-density lipoprotein cholesterol levels and all-cause mortality in patients with coronary artery disease: a real-world analysis using data from an international network.
Sci Rep
November 2024
The current cholesterol guidelines recommend maintaining low levels of low-density lipoprotein cholesterol (LDL-C) in patients with coronary artery disease (CAD). However, recent studies have suggested that both very low and very high LDL-C levels may be associated with increased mortality in the general population. We utilized data from TriNetX, a global health research network, to investigate the association between LDL-C levels and all-cause mortality in patients with CAD.
View Article and Find Full Text PDFBrazilian natural gas market dynamics: A data panel analysis of the Brazilian market compared with Argentina, Colombia, Mexico, and India using Porter's five forces framework.
Heliyon
November 2024
Article Synopsis
- - This study analyzes natural gas markets in Brazil, Mexico, Colombia, Argentina, and India from 2000 to 2020 using historical data and Porter's Five Forces to understand industry dynamics across different sectors.
- - It highlights Brazil's struggles with domestic production growth despite regulatory reforms and infrastructure efforts, indicating ongoing challenges in realizing sectoral expansion.
- - The research stresses the importance of policy improvements for better investment alignment and offers recommendations for stakeholders to navigate competitive landscapes and address potential market bottlenecks.