Real World Experience of Denosumab Treatment in the Belfast Osteoporosis Service.

Osteoporosis is a significant global health and economic burden associated with bone fracture, morbidity and mortality. Denosumab, a novel human monoclonal antibody second-line treatment, inhibits osteoclast-mediated bone resorption and increases bone mineral density (BMD). Treatment achieves reductions in vertebral, non-vertebral and hip fracture risk.

Publisher Correction: Assessing the efficiency of changes in land use for mitigating climate change.

In this Letter, the PANGAEA repository was referred to incorrectly in the 'Code availability' and 'Data availability' sections of Methods: the link should be https://doi.org/10.1594/PANGAEA.

Assessing the efficiency of changes in land use for mitigating climate change.

Land-use changes are critical for climate policy because native vegetation and soils store abundant carbon and their losses from agricultural expansion, together with emissions from agricultural production, contribute about 20 to 25 per cent of greenhouse gas emissions. Most climate strategies require maintaining or increasing land-based carbon while meeting food demands, which are expected to grow by more than 50 per cent by 2050. A finite global land area implies that fulfilling these strategies requires increasing global land-use efficiency of both storing carbon and producing food.

Europe's renewable energy directive poised to harm global forests.

This comment raises concerns regarding the way in which a new European directive, aimed at reaching higher renewable energy targets, treats wood harvested directly for bioenergy use as a carbon-free fuel. The result could consume quantities of wood equal to all Europe's wood harvests, greatly increase carbon in the air for decades, and set a dangerous global example.