Publications by authors named "T Quintanar"
Article Synopsis
- This study explores deregulated pathways and biological functions in human glioblastoma (GBM) by comparing gene expression in GBM patients to healthy brain tissue using a custom DNA microarray.
- The analysis identified 16 key genes that were either up-regulated or down-regulated in GBM, which were validated through RT-qPCR and used to create protein-protein interaction networks.
- The findings highlight the potential of these genes and their pathways as targets for innovative GBM therapies, suggesting that some compounds aimed at these genes are already in clinical use.
A consensus is needed among healthcare professionals involved in easing oncological pain in patients who are suitable candidates for intrathecal therapy. A Delphi consultation was conducted, guided by a multidisciplinary scientific committee. The 18-item study questionnaire was designed based on a literature review together with a discussion group.
View Article and Find Full Text PDFTreatment of oncological pain is complex and requires a multidisciplinary management approach between oncology services and pain units. Although significant improvements have been achieved in the treatment and overall survival of cancer patients, the management of oncological pain has not followed the same directions. Many patients are not referred to pain units even though they could benefit from it.
View Article and Find Full Text PDFBackground: There is a lack of knowledge about the career paths and employment situation of young medical oncologists. The aim of our study was to evaluate the current professional standing of these professionals in Spain.
Methods: The Spanish Society of Medical Oncology + MIR section conducted a national online survey in May 2021 of young medical oncology consultants (< 6 years of expertise) and final year medical oncology residents.
Purpose: The objectives of this project were to assess the current situation and management of cancer-related neuropathic pain (CRNP) in Spain and to provide specific recommendations for the assessment, diagnosis and treatment of CRNP using a Delphi methodology.
Methods: This was a qualitative study that followed a Delphi methodology using a questionnaire with 56 statements that were grouped into 5 areas related to CRNP: prevalence and impact, pathophysiology, assessment and diagnosis, specific syndromes, treatment, and multidisciplinary approach. Based on the responses, the scientific committee prepared an algorithm and a recommended pathway for the management of CRNP.