CPA4 overexpression correlates with poor prognosis and tumor progression in endometrial cancer.

Background: The rise in endometrial cancer rates globally calls for advanced diagnostic methods and new biomarkers. CPA4, known for its role in cancer development, has not yet been studied in relation to endometrial cancer, making it a promising research avenue.

Methods: We analyzed CPA4's mRNA expression using data from TCGA and GEO databases and validated these findings with 116 clinical samples through immunohistochemical analysis.

The underlying neurobiological basis of gray matter volume alterations in schizophrenia with auditory verbal hallucinations: A meta-analytic investigation.

Schizophrenia patients with auditory verbal hallucinations (AVH) frequently exhibit brain structural alterations, particularly reductions in gray matter volume (GMV).Understanding the neurobiological mechanisms underlying the changes is essential for advancing treatment strategies. To address this, a meta-analysis was conducted to identify GMV changes in schizophrenia patients with AVH and their associations with gene expression and neurotransmitter receptor profiles.

A near-infrared "turn-on" fluorescent probe for selective detection of copper(II) ions in aqueous media and its application in cell imaging.

Copper (II) is considered the third most essential trace element for life, following iron and zinc, and plays a vital role in various physiological and pathological processes. The fluorescent probe has become an important method for the detection of heavy metal ions. This investigation involved the development and synthesis of a near-infrared "turn-on" fluorescent probe, DCX-Cu, with a significant Stokes shift (156 nm), specifically to identify Cu compared other ions.

A simple post-processing approach induced Interface recombination to construct hollow cubic-shape Prussian blue analogs for biosensing and degradation of aflatoxins B1.

Multifunctional Prussian blue analogs (PBAs) have received extensive attention in the detection and degradation of food hazards. However, the development of new structural adjustment strategies to further improve their performance remains a huge challenge. Herein, the "interface recombination" post-processing approach was established to regulate the structure of PBAs using a microwave-assisted solvothermal method combined with acid etching.

Imaging and Pathology Concordance in Head and Neck Cancer: Retrospective Analysis.

Background: Lymph node metastasis critically impacts prognosis in head and neck malignancies. Preoperative imaging (CT/MRI) is vital for assessment but often yields false results. This study examines the concordance between preoperative imaging and postoperative pathology and identifies factors influencing imaging accuracy.