Publications by authors named "T Polte"
Polybrominated diphenyl ethers (PBDEs), commonly used as synthetic flame retardants, are present in a variety of consumer products, including electronics, polyurethane foams, textiles, and building materials. Initial evidence from epidemiological and experimental studies suggests that maternal PBDE exposure may be associated with a higher BMI in children, with disturbance of energy metabolism and an increased risk of Type 2 diabetes. However, the causality between early exposure to real-life PBDE concentrations and increased weight as well as mechanisms underlying impaired metabolic pathways in the offspring remain elusive.
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- The past decade has seen a rise in awareness and de-stigmatization of mental health issues, particularly concerning depression and anxiety, alongside increased diagnoses of neurodevelopmental disorders like ADHD and autism.
- Research suggests that early exposure to environmental chemicals may contribute to the development of these disorders, but findings regarding glyphosate, a common pesticide, remain inconclusive.
- A study using a mouse model found that maternal glyphosate exposure during pregnancy and breastfeeding led to anxiety-like behaviors and changes in gut microbiota in female offspring, indicating potential impacts on the gut-brain axis.*
Exposure to environmental pollutants via food, particularly during the prenatal and early postnatal periods, has been linked to adverse effects on the immune system. Among these pollutants, the widely used pesticide glyphosate has been associated with endocrine disruption, autism, and cancer. Occupational high exposure to glyphosate has also been shown to influence immune function and exacerbate allergic asthma.
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- Parabens are common preservatives in cosmetics and food, with studies indicating that exposure during early life may affect immune responses and allergy risk, though their impact on asthma remains unclear.* -
- Research involving both mice and humans found that while certain parabens could either reduce or promote asthma development based on exposure timing, multiple paraben exposure does not appear to have a negative effect on asthma in children.* -
- The findings suggest the need to differentiate between individual and combined paraben exposures in assessing potential risks for asthma, emphasizing the importance of when the exposure occurs.*
Mold, Mycotoxins and a Dysregulated Immune System: A Combination of Concern?
Int J Mol Sci
November 2021
Fungi represent one of the most diverse and abundant eukaryotes on earth. The interplay between mold exposure and the host immune system is still not fully elucidated. Literature research focusing on up-to-date publications is providing a heterogenous picture of evidence and opinions regarding the role of mold and mycotoxins in the development of immune diseases.
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